โ GSK GlaxoSmithKlineโ๏ธ Cold Chain๐ฉโโ๏ธ Certified Nurse๐งฌ Live Attenuated๐ Subcutaneous/IM
Priorix is a live attenuated combination vaccine manufactured by GlaxoSmithKline (GSK), protecting against measles, mumps and rubella in a single injection. It uses the Schwarz strain for measles, the RIT 4385 strain (derived from Jeryl Lynn strain) for mumps, and the Wistar RA 27/3 strain for rubella. Available at VacciHub at โน995 per dose with home vaccination across Delhi NCR by certified nurses with end-to-end cold chain guarantee.
๐งฌ 3 Diseases Prevented in One Shot โ All Live Attenuated Strains in Priorix
Measles
Schwarz Strain
Produced in chick embryo cells
NLT 10ยณโ โฐ CCIDโ โ per 0.5 mL dose
Mumps
RIT 4385 Strain (from Jeryl Lynn strain)
Produced in chick embryo cells
NLT 10ยณโ โท CCIDโ โ per 0.5 mL dose
Rubella
Wistar RA 27/3 Strain
Produced in human diploid (MRC-5) cells
NLT 10ยณโ โฐ CCIDโ โ per 0.5 mL dose
* CCIDโ โ = Cell Culture Infective Dose 50% ยท Live attenuated ยท Reconstituted with Water for Injections IP ยท GSK
๐ฅ Who Should Get Priorix
Priorix is recommended as part of the national and IAP childhood immunization schedule, and is important for several other groups too:
๐ถ
Infants & Children (9โ18 months)
First dose at 9โ12 months, second dose at 15โ18 months as per the IAP/national immunization schedule. Protects against three serious childhood viral infections in a single injection.
๐ง
Older Children & Adolescents
Catch-up doses are recommended if the primary schedule was missed, delayed or incomplete. Two doses at least 4 weeks apart are needed for full protection.
๐ง
Adults Without Documented Immunity
Adults with no record of MMR vaccination or natural infection should receive 2 doses, particularly healthcare workers, teachers and those in shared living settings.
๐คฐ
Women Planning Pregnancy
Rubella infection during pregnancy can cause serious birth defects. Vaccination should be completed at least 1 month before conception โ Priorix cannot be given during pregnancy itself.
โ๏ธ
International Travellers
Measles outbreaks continue to occur worldwide. Travellers without documented MMR immunity should be vaccinated at least 2 weeks before international travel.
๐ฅ
Healthcare Workers
Staff in clinical settings are at higher risk of exposure to measles, mumps and rubella. Annual health checks and documented MMR immunity are commonly required by hospitals.
๐ฌ Priorix Composition โ Per 0.5 mL Dose
After reconstitution, each 0.5 mL dose contains, as per GSK manufacturer specifications:
Component
Quantity
Notes
ACTIVE INGREDIENTS โ 3 LIVE ATTENUATED STRAINS
Measles virus (Schwarz strain)
NLT 10ยณโ โฐ CCIDโ โ
Produced in chick embryo cells
Mumps virus (RIT 4385 strain, derived from Jeryl Lynn strain)
NLT 10ยณโ โท CCIDโ โ
Produced in chick embryo cells
Rubella virus (Wistar RA 27/3 strain)
NLT 10ยณโ โฐ CCIDโ โ
Produced in human diploid (MRC-5) cells
EXCIPIENTS & DILUENT
Stabilisers and freeze-drying agents
As per manufacturer label
Freeze-dried powder
Solvent (diluent)
Water for Injections IP, qs 0.5 mL
Supplied in pre-filled syringe
Figures are as per the GlaxoSmithKline (GSK) manufacturer package insert available at the time of publishing. Please refer to the current package insert for confirmation.
โ ๏ธ Allergy note: Priorix components are produced in chick embryo cells and may contain trace neomycin. Persons with known severe allergy to neomycin or egg protein should inform the VacciHub nurse before vaccination. Our nurses conduct pre-vaccination health screening before every dose.
๐ Priorix Vaccination Schedule
Age Group
Number of Doses
Timing
Notes
Infants & Children (routine schedule)
2 Doses
Dose 1 at 9โ12 months, Dose 2 at 15โ18 months
As per IAP/national immunization schedule
Older children/adolescents (catch-up)
2 Doses
At least 4 weeks apart
If primary schedule missed or incomplete
Adults without documented immunity
2 Doses
At least 4 weeks apart
Includes healthcare workers, travellers, teachers
Women planning pregnancy
2 Doses
Complete at least 1 month before conception
Not to be given during pregnancy
๐ก Route of administration: Subcutaneous or intramuscular injection, typically into the upper arm (deltoid) or anterolateral thigh in infants. Our VacciHub certified nurses ensure correct injection technique for all age groups.
โ ๏ธ Storage requirements: Priorix must be stored and transported refrigerated at 2ยฐC to 8ยฐC. Do NOT freeze. Store in the original package to protect from light. VacciHub nurses transport Priorix in validated cold-chain boxes with temperature data loggers.
โ๏ธ How Does Priorix Work?
1
Live Attenuated Virus Injected
0.5 mL of reconstituted Priorix is injected subcutaneously or intramuscularly. The dose delivers weakened (attenuated) measles, mumps and rubella viruses that can replicate briefly but are too weak to cause the actual diseases in healthy, immunocompetent individuals.
2
Mild Immune Activation
The weakened viruses trigger the immune system to mount a response, similar to a natural infection but without the severity. This is why mild fever or rash may sometimes appear 5โ12 days after vaccination โ this is expected and not the actual disease.
3
Antibody & Memory Cell Formation
The immune system produces antibodies specific to measles, mumps and rubella, along with long-lived memory B-cells and T-cells that can recognise and fight these viruses in the future.
4
Long-Lasting Protection After 2 Doses
A single dose provides good protection, but a completed 2-dose schedule provides strong, long-lasting immunity against all three viral infections and their complications, and is considered protective for life in most people.
โ Cannot cause the natural disease in healthy people: Priorix uses highly weakened, attenuated strains โ it does not cause measles, mumps or rubella disease in healthy, immunocompetent individuals. Mild vaccine-related symptoms like low-grade fever or a faint rash are normal immune activation responses, not the actual infection. Live vaccines like Priorix are not given to individuals with severe immunodeficiency โ see Precautions below.
โ ๏ธ Priorix Side Effects
Priorix has a well-established safety record built over more than two decades of global use. Most reactions are mild and self-limiting.
Common (Injection Site & Mild)
Pain, redness and swelling at the injection site; mild fever; irritability in infants.
Less Common (1โ3 Weeks Later)
Mild measles-like rash; transient joint pain or swelling (more common in adult women); mild swelling of the parotid glands.
Rare
Febrile seizures (uncommon, usually benign); temporary low platelet count (thrombocytopenia).
Seek Medical Attention Immediately
๐ค Severe allergic reaction (neomycin/egg protein)
๐ต Syncope (fainting) post-injection
๐ง Encephalitis โ extremely rare
๐จ Anaphylaxis (extremely rare)
๐ก Post-vaccination care: Remain seated for 15โ30 minutes after injection. Paracetamol (acetaminophen) can be taken for fever or discomfort per doctor's advice. Watch for rash or joint symptoms over the following 1โ3 weeks. Our VacciHub nurses monitor all patients post-vaccination before leaving.
โ๏ธ Priorix vs Other MMR Vaccines Available in India
Feature
Priorix (GSK)
Zyvac MMR (Zydus)
Tresivac PFS (Serum Institute)
Measles strain
Schwarz
Edmonston-Zagreb
Edmonston-Zagreb
Mumps strain
RIT 4385 (Jeryl Lynn derivative)
Hoshino
L-Zagreb
Rubella strain
Wistar RA 27/3
RA 27/3
Wistar RA 27/3
Manufacturer
GSK (GlaxoSmithKline)
Zydus Lifesciences
Serum Institute of India
MRP (per dose)
โน995
โน895
โน814
VacciHub Price
โ โน995
โน895
โน814
โน๏ธ Which MMR vaccine should I choose? All three are effective, WHO-compliant MMR combination vaccines with a similar safety profile. Priorix is a well-established GSK option used widely in national immunization programmes globally. Zyvac MMR and Tresivac PFS are trusted Indian-manufactured alternatives at a lower price point. Consult VacciHub for personalised guidance based on your child's or family's vaccination history.
๐ซ Precautions and Contraindications
Do NOT give Priorix if:
Known severe allergic reaction to a previous dose, neomycin, or egg protein
Currently pregnant, or planning pregnancy within 1 month of vaccination
Severe immunodeficiency (e.g. leukaemia, lymphoma, high-dose steroids, untreated HIV with severe immunosuppression)
Active untreated tuberculosis
Moderate to severe acute illness or high fever โ defer until recovered
Recent receipt of blood products, immunoglobulins or another live vaccine โ inform your VacciHub nurse to check spacing requirements
โ ๏ธ Being a live vaccine: Priorix must not be given to individuals with severe immunodeficiency, as the weakened viruses could theoretically cause illness in someone whose immune system cannot control them. Always disclose your full medical history to the VacciHub nurse before vaccination.
๐ฅ Why Book Priorix with VacciHub?
๐ฉโโ๏ธ
Certified Nursing Staff
Trained, certified nurses for infants, children and adults. Correct subcutaneous/IM injection technique. Pre-vaccination health check and history review included with every home visit.
โ๏ธ
End-to-End Cold Chain
Priorix transported in validated cold-chain boxes with temperature data loggers, maintaining 2โ8ยฐC from our storage to your home, protecting vaccine potency.
๐จโ๐ฉโ๐งโ๐ฆ
Whole Family in One Visit
Book Priorix for your child along with other due vaccines for siblings, parents or grandparents โ one nurse visit covers everyone.
๐ฐ๏ธ
Same-Day and Weekend Slots
Flexible bookings morning to evening, 7 days a week including public holidays. Same-day appointments available in most Delhi NCR areas.
๐ Priorix Home Vaccination โ Cities We Serve
๐๏ธDelhi (All Areas)
๐๏ธGurgaon
๐Noida
๐๏ธGhaziabad
๐๏ธFaridabad
๐Greater Noida
Call +91 92050 04114 to confirm service availability for your specific pincode โ same-day slots available in most areas.
โ Frequently Asked Questions
Priorix is a live attenuated combination vaccine by GlaxoSmithKline (GSK) that protects against measles, mumps and rubella in a single injection, using the Schwarz measles strain, RIT 4385 mumps strain and Wistar RA 27/3 rubella strain.
The MRP of Priorix at VacciHub is โน995 per dose, which also includes a certified nurse home visit for your location across Delhi NCR.
Children need 2 doses โ the first at 9โ12 months and the second at 15โ18 months. Adults and adolescents without documented immunity typically need 2 doses at least 4 weeks apart.
No. Priorix is a live vaccine and must not be given during pregnancy. Women planning pregnancy should complete vaccination at least 1 month before conception.
All three are effective MMR combination vaccines. Priorix (GSK) uses the Schwarz measles and RIT 4385 mumps strains; Zyvac MMR (Zydus) uses the Edmonston-Zagreb measles and Hoshino mumps strains; Tresivac PFS (Serum Institute) uses the Edmonston-Zagreb measles and L-Zagreb mumps strains. See the comparison table above for pricing and details.
Yes. VacciHub provides home vaccination with Priorix across Delhi (all areas), Gurgaon, Noida, Ghaziabad, Faridabad and Greater Noida. A certified nurse comes to your home with genuine GSK Priorix at 2โ8ยฐC cold chain. Call +91 92050 04114 or WhatsApp to book your appointment.
Most people experience only mild injection-site pain, redness or low-grade fever. Some people develop a mild rash or joint pain 1โ3 weeks after vaccination โ this is a normal, expected immune response and not measles, mumps or rubella infection. Serious reactions are rare.