

Routine Tdap booster every 10 years to maintain protection against diphtheria, tetanus and pertussis
Recommended in every pregnancy to pass protective antibodies to the newborn against whooping cough
Reduces transmission risk to infants and vulnerable patients in clinical settings
Ensures updated tetanus and pertussis protection before international travel
Booster dose recommended after a deep or contaminated injury if last dose was over 5 years ago
Family members and caregivers of infants should be vaccinated to prevent whooping cough transmission (cocooning)
| Component | Details |
|---|---|
| Active Antigens | Diphtheria toxoid (≥2 IU), Tetanus toxoid (≥20 IU), Acellular Pertussis antigens (Pertussis toxoid, FHA, Pertactin) |
| Adjuvant | Aluminium hydroxide / aluminium phosphate |
| Preservative | Preservative-free formulation |
| Presentation | 0.5 mL pre-filled syringe, single dose |
| Route | Intramuscular injection (deltoid muscle) |
| Storage | 2°C – 8°C, protect from light, do not freeze |
| Group | Doses | Timing |
|---|---|---|
| Adolescents & Adults (routine booster) | 1 Dose | Every 10 years |
| Pregnancy | 1 Dose | Each pregnancy, 27–36 weeks gestation |
| Wound Management | 1 Dose | If last Td/Tdap dose was >5 years ago |
The dTpa antigens are administered via intramuscular injection into the deltoid muscle.
The immune system recognises the diphtheria, tetanus and pertussis antigens without causing disease.
Protective antibodies against all three diseases are generated within about 2 weeks.
Immunity is reinforced, maintaining protection against diphtheria, tetanus and pertussis for approximately 10 years.
| Boostrix (GSK) | T.D.VAC (Serum Institute) | TETRAXIM (Sanofi) | |
|---|---|---|---|
| Type | dTpa — includes Pertussis | Td only — no Pertussis | DTaP-IPV — paediatric combination |
| Pertussis Protection | Yes | No | Yes |
| Recommended For | Adolescents & adults, pregnancy | Wound / tetanus-only booster | Children under 7 years |
| Route | Intramuscular | Intramuscular | Intramuscular |
| Price on VacciHub | ₹1,690.00 | ₹100.00 | ₹2,635.00 |
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